Full Prescribing Information and Instructions for Use
ENGLISH ESPAÑOL
For Patients and Caregivers
Kineret and IL-1 Patient Insights Kineret RA Data Kineret NOMID Data KINERET® On TRACK Practice Support

A team of experts supporting you and your patients.

KINERET® On TRACK Case Managers, Pharmacy Specialists, and Kineret Trained Nurses are here to help care for your patients.

Our team of Kineret experts includes Case Managers, Pharmacy Specialists, and Kineret Trained Nurses. They are here to help support you, your team, and your patients by providing assistance with prescription delivery, insurance, and reimbursement; and answers to some of their Kineret-related questions.

Contact us directly or call your Clinical Account Manager to learn more.

Call us: 866.547.0644

8AM to 8PM EST, Monday through Friday

KINERET On TRACK resources

KINERET On TRACK referral form

Referral form for the KINERET On TRACK program. Also serves as your patient's Kineret prescription


KINERET Patient Assistance Program application form

This form has sections to be filled out by healthcare professionals and patients to determine eligibility for the Kineret patient financial assistance program

Kineret Case Managers

Kineret Case Managers may be able to guide you and your patients through the insurance approval process and help find access solutions.

Case Managers can help with:

  • Benefits investigations
  • Insurance coverage verification
  • Prior Authorization support
  • Appeals support

Financial assistance programs:

  • A Co-Pay Program that offers up to $10,000 annually to reduce out-of-pocket costs to no more than $25 per shipment for eligible commercially insured patients*
  • A Patient Assistance Program that can help eligible uninsured and underinsured patients access Kineret free of charge*

*Patients must be US citizens or legal residents under the care of a licensed practicing healthcare provider and prescribed Kineret. Other terms and conditions apply.


Kineret Pharmacy Specialists

Kineret Pharmacy Specialists will deliver your patient’s prescription right to their door. The first time. And every time.

Pharmacy Specialist services include:

  • Prescription delivery directly to patients’ homes
  • Free sharps containers and needle clippers
  • Refill reminders
  • Emergency shipments
  • Information about Kineret

RxCrossroads is the specialty pharmacy that fills and ships Kineret prescriptions.


Kineret Trained Nurses

Kineret Trained Nurses can help your patients understand how to use Kineret, with your direction.

Nurse services include:

  • One-on-one injection training and in-home visits
  • Tips to help address common injection site reactions
  • Advice on injection site rotation and tracking
  • Helpful insights on issues from medication storage to travel

KINERET On TRACK Guidance

Patients can sign up for KINERET On TRACK Guidance to receive extra support.

KINERET On TRACK Guidance offers:

  • Personalized communications from our team of experts to help your patients get started
  • Educational materials that help them know what to expect
  • Online resources packed with useful information

INDICATION

Kineret® is an interleukin-1 receptor antagonist indicated for:

Rheumatoid Arthritis (RA)

  • Reduction in signs and symptoms and slowing the progression of structural damage in moderately to severely active rheumatoid arthritis, in patients 18 years of age or older who have failed 1 or more disease-modifying antirheumatic drugs (DMARDs)

Cryopyrin-Associated Periodic Syndromes (CAPS)

  • Treatment of Neonatal-Onset Multisystem Inflammatory Disease (NOMID)

IMPORTANT SAFETY INFORMATION

  • Kineret is contraindicated in patient with known hypersensitivity to E. coli-derived proteins, Kineret, or to any components of the product
  • In RA, discontinue use if serious infection develops. In Kineret-treated NOMID patients, the risk of a NOMID flare when discontinuing Kineret treatment should be weighed against the potential risk of continued treatment. Do not initiate Kineret in patients with active infections
  • Use in combination with Tumor Necrosis Factor (TNF) blocking agents is not recommended
  • Hypersensitivity reactions, including anaphylactic reactions and angioedema, have been reported
  • The impact of treatment with Kineret on active and/or chronic infections and the development of malignancies is not known
  • Live vaccines should not be given concurrently with Kineret
  • Neutrophil counts should be assessed prior to initiating Kineret treatment, and while receiving Kineret, monthly for 3 months, and thereafter quarterly for a period up to 1 year
  • RA: Most common adverse reactions (incidence ≥ 5%) are injection site reaction, worsening of rheumatoid arthritis, upper respiratory tract infection, headache, nausea, diarrhea, sinusitis, arthralgia, flu-like symptoms, and abdominal pain
  • NOMID: The most common AEs during the first 6 months of treatment (incidence > 10%) are injection site reaction, headache, vomiting, arthralgia, pyrexia, and nasopharyngitis
  • A higher rate of serious infections has been observed in RA patients treated with concurrent Kineret and etanercept therapy than in patients treated with etanercept alone. Use of Kineret in combination with TNF blocking agents is not recommended
  • Because there is a higher rate of infections in the elderly population in general, caution should be used in treating the elderly
  • Kineret is substantially excreted by the kidney, and the risk of toxic reactions to Kineret may be greater in patients with impaired renal function

Please see full Prescribing Information.